Use of Anticonvulsants During Pregnancy: Teratogenic Risks
نویسنده
چکیده
The chapter summarizes literature on the teratogenic effects of anticonvulsants and presents data from the Swedish Medical Birth Register. Many anticonvulsants have a teratogenic effect which varies between individual drugs with the highest risk associated with the use of valproic acid and probably topiramide. For some much used drugs like carbamazepine and lamotrigine the risk is not much elevated. Polytherapy is associated with a higher risk than monotherapy and again use of valproic acid is the strongest risk factor.
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